Blood Group Antigen Lewis A
Stomach tissue stained with Anti-
Blood group antigen Lewis A using
AEC chromogen
| Clone | : | 7LE |
| Isotype | : | IgG1 |
| Immunogen | : | Mucin isolated from ovarian cyst fluid |
| Source | : | Mouse |
| Specificity | : | Blood group antigen Lewis A |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | STOMACH |
| Pretreatment | : | None |
| Intended Use | : | IVD |
Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Enhanced expression of Lewis A antigen has been found in malignant transformation of gastric tissues. A panel of antibodies to Lewis antigens, including Lewis A, Lewis B and sialylated Lewis A, is useful in the immunopathological analysis of gastric cancers. Clone 7LE detects Lewis A antigen in cultured cells and tissue sections by immunohistochemistry and reacts with the immunogen in ELISA assays. This antibody stains blood group antigen Lewis A.
