Collagen III
Skin tissue stained with Anti-Collagen III using AEC chromogen
| Clone | : | HWD1.1 |
| Isotype | : | IgG |
| Immunogen | : | Human collagen purified by high performance liquid chromatography |
| Source | : | Mouse |
| Specificity | : | Collagen type III |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | SKIN |
| Pretreatment | : | Pepsin |
| Intended Use | : | IVD |
Collagen type III is a marker for interstitial connective tissue of the extracellular matrix. Collagen type III is diffusely present throughout the interstitial connective tissues making it a better marker than cellular fibronectin which is more closely associated with basement membrane and presence in extracellular matrix is minimal. In highly specialized vascular beds of spleen and glomeruli where basement membrane is prominent, little collagen type III is detected, whereas fibronectin is abundant. This antibody does not react with collagens type I, II, IV, V, VI, or VII. This antibody stains positive for Collagen type III in interstitial
connective tissue but not on basement membranes.
