CD10
CD10 expression in a reactive node
stained using DAB chromogen
| Clone | : | 56C6 |
| Isotype | : | IgG1 |
| Immunogen | : | Human CD10 |
| Source | : | Mouse |
| Specificity | : | CD10 Surface Ag |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | Lymphoma |
| Pretreatment | : | EZ-AR™ 1 |
| Intended Use | : | IVD |
CD10, a 100 KD glycoprotein, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and chronic myelogenous leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, with especially high expression on the brush border of kidney and gut epithelial cells.
