Alpha-1-Antichymotrypsin
Liver stained with Alpha-1-Antichymotrypsin antibody using AEC chromogen
| Clone | : | α1A88 |
| Isotype | : | IgG1, Kappa |
| Immunogen | : | Biochemically purified alpha-1-antichymotrypsin protein was used to sensitize Balb/c (H-2d) mice. Clone α1A88 was developed through a standard hybridoma technology procedure |
| Source | : | Mouse |
| Specificity | : | Alpha-1-Antichymotrypsin protein |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | LIVER CARCINOMA |
| Pretreatment | : | None |
| Intended Use | : | IVD |
Alpha-1-Antichymotrypsin (ACT) is a serine protease inhibitor. It forms a complex with serine protease, a prostate-specific antigen in human serum. ACT can be found in most cells of myeloid lineage and is, therefore, useful in the identification of neoplastic myeloid cells within extramedullary tissues such as acute myeloid leukemia. This enzyme is also localized in the spindle cells and round cells of true histiocytic lymphomas as well as in most thyroid papillary carcinomas. ACT is expressed in various normal and neoplastic cells. The mouse monoclonal antibody stains ACT protein in the cytoplasm of many different cells.
