Apolipoprotein E
Hepatocellular carcinoma stained
with Anti-ApoE using DAB as
chromogen
| Clone | : | EP1373Y |
| Isotype | : | IgG |
| Immunogen | : | A synthetic peptide corresponding to residues near the N-term of human apolipoprotein E |
| Source | : | Rabbit |
| Specificity | : | Apolipoprotein E |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | Liver |
| Pretreatment | : | AR Citra Plus |
| Intended Use | : | IVD |
Apolipoprotein E (ApoE) is essential for the normal catabolism of triglyceride rich lipoprotein constituents. Defects in the ApoE gene will result in familial dysbetalipoproteinemia or type III hyperlipoproteinemia and will increase cholesterol and triglycerides levels in the blood. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes. There are three isoforms of the ApoE lipoprotein, known as ApoE2, E3 and E4. ApoE4 has been associated to increase probability of developing Alzheimer disease.
