Cytokeratin 20
Colon carcinoma stained with anti-CK20 using DAB as chromogen
| Clone | : | EPR1622Y |
| Isotype | : | IgG |
| Immunogen | : | A synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 20 was used as an immunogen |
| Source | : | Rabbit |
| Specificity | : | Cytokeratin 20 |
| Protocol | : | 30 min @ RT |
| Tissue type | : | FFPE |
| Control tissue | : | Colon Carcinoma Tissue |
| Pretreatment | : | AR Citra Plus |
| Intended Use | : | IVD |
Keratins are intermediate filaments expressed by epithelial cells that are involved in cell movement, differentiation, and mitosis. Cytokeratin 20 (CK20) primarily found in the goblet cells and enterocytes of gastric and intestinal mucosa. CK20 is expressed in colorectal, pancreatic, bile duct adenocarcinomas, and transitional cell carcinoma of the bladder. When used in a panel with CK7, CK20 can be particularly useful in identifying colorectal adenocarcinomas and differentiating it from other metastatic carcinomas and also identifying metastatic colorectal adenocarcinmas
