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Clinical Platforms

BioGenex is a pioneer in the design, development and manufacturing of advanced systems for automation of cell and tissue-based staining. To accommodate diverse laboratory needs, we offer three different clinical automation platforms for in-vitro diagnostic applications. These platforms support LIMS connectivity, meet globally accepted quality standards (ISO13485:2003 & ISO9001:2008) and are approved for IVD use in the US by the FDA, and in Europe with CE marking.

 

1. Xmatrx Automated Staining Systems (ELITE, ULTRA Dx):

The Xmatrx systems offer standardized processes from baking through final glass cover slip in three simple steps: load, click and view. These systems are FDA approved for In Vitro Diagnostic (IVD) applications including: immuno-histochemistry (IHC), in situ hybridization (ISH), co-detection and special staining. The Xmatrx systems are equipped with eXACT™ Temperature Control active heating and cooling units on every slide, Barcode enabled technologies, disposable pipette tips to prevent cross-contamination of reagents and an on-board cover slipping function.

 

Features & Benefits

  • 40 independent protocols simultaneously
  • Fully Automated, including Baking, Dewaxing & Antigen Retrieval
  • eXACT™ Temperature Control on Every Slide (RT-105oC)
  • Bar-Coded reagent vials and slides to eliminates human errors
  • Wide reagent dispense volumes: 10 µL to 850 µL
  • BioGenex’s proprietary coverslip mechanism
  • Over 400+ optimized protocols with ready to use reagents
  • LIMS - enabled data tracking and management
  • Liquid level sensor for accurate reagent dispensing
  • System allows use of 3rd party antibodies

 

2. i6000 Elite Dx Automated Staining Systems:

The i6000 Elite Dx is a high-throughput system for IHC and Special Staining of clinical samples in molecular pathology laboratories. The i6000 has a staining capacity of 200 slides in 8 hours (60 slides in 3 hours). The system is supplied together with the EZ-Retriever® for Microwave-based Dewaxing and Antigen Retrieval, and the i500 Plus LIMS enabled, Barcode Label Printer. The i6000 has a predictable cost structure and short learning curve to enhance cross training and personnel rotation. We have optimized more than 400 protocols assuring clean, intense and reproducible staining results.

Features & Benefits

  • Clean, crisp and intense stains
  • High throughput – Up to 200 slides in eight-hour shift, 60 slides in 3 hours
  • Over 400+ optimized protocols with ready-to-use reagents in barcoded vials
  • Dispense reagents as low as 100μL/slide
  • Multiple slide processing options - Random, Continuous and STAT
  • Multi-format specimen processing - FFPE or frozen tissues, cell preparations, fine needle aspirates, smears and more…
  • Color-coded GUI with real-time assay parameter display for all slides
  • Customized or standard reports for inventory management and regulatory compliance and submission

 

EZ-Retriever®

Programmable microwave oven with built in temperature control

Clinical Platform

  • High Throughput - 96 Slides / 35 minutes
  • Greater reproducibility Dewaxing, Rehydration, and Antigen Retrieval
  • Preserved tissue morphology with fast uniform heating and cooling of AR solutions
  • Optimized factory protocols for convenience and consistent results
  • AR solutions are non-hazardous, non- flammable and odorless
  • Compliance to applicable CLSI (Clinical and Laboratory Standards Institute) guidelines

i500 Plus

LIMS Enabled Barcode Label Printer

Clinical Platform
  • For printing chemical resistant barcode labels
  • Compatible with Xmatrx and i6000
  • User-friendly software
  • Synchronization of protocol information

 

Specifications Xmatrx ULTRA Dx Xmatrx ELITE i6000 Elite Dx
Automation Full (baking through cover slip) Full (baking through cover slip) Automated. Supplied with EZ-Retriever® for Dewax & Antigen retrieval
Run Time (full slide load) 5.5 hours 5.5 hours 2.5 hours
Throughput (8 hours) 60 slides 60 slides 200 slides
Temperature Range Ambient to 105oC Ambient to 105oC NA
Reagent Dispensing Volume 10-850 µl 10-850 µl 100-1000 µl
Slide Capacity 40 40 60
Reagent Capacity 42 49 60
Reader Barcode Barcode Barcode
Bulk Reagent Carboy 7 x 4 L 7 x 4 L 2 x 10 L
Waste Container 20 L 8 L 20 L
Languages enabled English English English, Chinese, German
LIMS - enabled data tracking and management
Protocols >400, preloaded >400, preloaded >400, preloaded
Dimensions (D/W/H) 30”/43”/54” 29”/46”/59” 24”/40.5”/18.5”
Weight 419 lb / 190 kg 400 lb/ 182 kg 130 lb / 59 kg

 

Clinical Platforms /Application

IHC

ISH/CISH

Double Staining

Special Stains

IF

Xmatrx® ELITE

Xmatrx® ULTRA Dx

i6000TM Elite DX

NA

 

Clinical Platforms