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Anti CDX2 Antibody for Colon Tumor Diagnosis

BioGenex presents anti CDX2 antibody for Colon tumor diagnosis. CDX2 (Caudal Type Homeobox 2) is a homeobox domain-containing transcription factor belongs to murine CDX family. It is an important protein in intestinal development, anterior to posterior patterning of the intestinal epithelium, proliferation and maintenance of the intestinal phenotype.
Expression of CDX2 is observed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach, and intestinal-type gastric cancer. CDX2 loss promotes metastasis in CRC through a CDX2-dependent mechanism. Loss of CDX2 expression is associated with advanced stage, higher tumor grade, presence of lymphovascular space invasion, worse progression-free survival, reduced overall survival and thereby functions as a poor prognostic factor in CRC.
BioGenex offers ready-to-use (RTU) & concentrated forms of antibodies for both manual & automated systems which are best-in-class for clinicopathological diagnosis & drug discovery. It enables pathologists & clinicians to precisely diagnose and improve life expectancy.

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