Diagnostic Instruments
BioGenex is a pioneer in the design, development and manufacturing of advanced systems for automation of cell and tissue-based staining. To accommodate diverse laboratory needs, we offer three different clinical automation platforms for in-vitro diagnostic applications. These platforms support LIMS connectivity, meet globally accepted quality standards (ISO13485:2003 & ISO9001:2008) and are approved for IVD use in the US by the FDA, and in Europe with CE marking.
1. Xmatrx® Automated Staining Systems:
The Xmatrx systems offer standardized processes from baking through final glass cover slip in three simple steps: load, click and view. These systems are FDA approved for In Vitro Diagnostic (IVD) applications including: immuno-histochemistry (IHC), in situ hybridization (ISH), co-detection and special staining. The Xmatrx systems are equipped with eXACT™ Temperature Control active heating and cooling units on every slide, RFID and Barcode enabled technologies, disposable pipette tips to prevent cross-contamination of reagents and an on-board cover slipping function.
Features & Benefits
- 40 independent protocols performed simultaneously
- Fully Automated System from Microtome to Microscope, including Baking, Dewaxing and Antigen Retrieval
- eXACT™ Temperature Control on Every Slide (RT-105oC)
- RFID tagged reagent vials together with Barcoded slides, eliminates human errors
- Wide range of reagent dispense volumes: 10 μL to 850 μL
- BioGenex’s proprietary coverslip mechanism
- Over 400+ optimized protocols with ready to use reagents in RFID tagged vials
- LIMS - enabled data tracking and management
- Liquid level sensor for accurate reagent dispensing
- Allows use of 3rd party antibodies
2. i6000™ Diagnostics Automated Staining Systems:
The i6000 Elite Dx is a high-throughput system for IHC and Special Staining of clinical samples in molecular pathology laboratories. The i6000 has a staining capacity of 200 slides in 8 hours (60 slides in 3 hours). The system is supplied together with the EZ-Retriever® for Microwave-based Dewaxing and Antigen Retrieval, and the i500 Plus LIMS enabled, Barcode Label Printer. The i6000 has a predictable cost structure and short learning curve to enhance cross training and personnel rotation. We have optimized more than 400 protocols assuring clean, intense and reproducible staining results.
Features & Benefits
- High capacity: 60 slides and 53 antibodies per run. 200 slides in 8 hours
- Works seamlessly with EZ-Retriever® for Eco-friendly De-waxing, Rehydration and Antigen Retrieval
- Barcoded slides and reagent vials to minimize hands-on time and data entry errors
- Wide range of reagent dispense volumes: 100 μL to 900 μL
- Over 400 optimized protocols with ready to use reagents in barcoded vials
- LIMS - enabled data tracking and management
- Liquid level sensor for accurate reagent dispensing
- Allows use of 3rd party antibodies
3. EZ-Retriever® System
Programmable microwave oven with built in temperature control
- High Throughput - 96 Slides / 35 minutes
- Greater reproducibility Dewaxing, Rehydration, and Antigen Retrieval
- Preserved tissue morphology with fast uniform heating and cooling of AR solutions
- Optimized factory protocols for convenience and consistent results
- AR solutions are non-hazardous, non- flammable and odorless
- Compliance to applicable CLSI (Clinical and Laboratory Standards Institute) guidelines
4. i500 Plus™
LIMS Enabled Barcode Label Printer

- For printing chemical resistant barcode labels
- Compatible with Xmatrx and i6000
- User-friendly software
- Synchronization of protocol information
Specifications | Xmatrx® ULTRA Dx* | Xmatrx® ELITE | i6000™ Diagnostics |
Automation | Full (baking through cover slip) | Full (baking through cover slip) | Automated. Supplied with EZ-Retriever® for Dewax & Antigen retrieval |
Run Time (full slide load) | 5.5 hours | 5.5 hours | 2.5 hours |
Throughput (8 hours) | 60 slides | 60 slides | 200 slides |
Temperature Range | Ambient to 105oC | Ambient to 105oC | NA |
Reagent Dispensing Volume | 10-850µl | 10-850 µl | 100-1000 µl |
Slide Capacity | 40 | 40 | 60 |
Reagent Capacity | 42 | 49 | 60 |
Reader | Barcode | Barcode | Barcode |
Bulk Reagent Carboy | 7 x 4 L | 7 x 4 L | 2 x 10 L |
Waste Container | 20 L | 8 L | 20 L |
Languages enabled | English | English | English, Chinese, German |
LIMS - enabled data tracking and management | ✓ | ✓ | ✓ |
Protocols | >400, preloaded | >400, preloaded | >400, preloaded |
Dimensions (D/W/H) | 30”/43”/54” | 29”/46”/59” | 24”/40.5”/18.5” |
Weight | 419 lb / 190 kg | 400 lb/ 182 kg | 130 lb / 59 kg |
Clinical Platforms /Application |
IHC |
ISH/CISH |
Double Staining |
Special Stains |
IF |
Xmatrx® ELITE |
✓ |
✓ |
✓ |
✓ |
✓ |
Xmatrx® ULTRA Dx |
✓ |
✓ |
✓ |
✓ |
✓ |
i6000TM Elite DX
|
✓ |
NA |
✓ |
✓ |
✓ |
* Xmatrx Ultra will be launched soon