C4d (Complement 4d) is the final proteolytic remnant of the activated complement factor C4b. C4 is a component of the classical complement cascade, which is typically initiated by binding of antibodies to specific target molecules. The expression of C4d in peritubular capillaries is a crucial sign for acute humoral (i.e. antibody-mediated) rejection of kidney, pancreas, heart and lung allografts. Anti-C4d is considered as an important biomarker in organ transplants and used in the diagnosis of Acute Rejection and aggressive anti-rejection treatment.
SKU: AMD36GP-1-1
Intended Use: IVD
Antibody Type: Cytoplasm
Clone: SPM545
Source: Mouse
Tissue Type/Cancer Type: Tonsil tissues