BioGenex Launches New Antibodies for Cancer Diagnostics

21 Aug

BioGenex, a pioneer in automated staining solution provider for cancer diagnostics announces the launch of five new primary antibodies for cancer immunohistochemistry (IHC).

With our Super Sensitive Detection System, our IHC solution offers the widest portfolio with over 400 primary antibodies, reagents, consumables, and ancillaries.

Included in the launch are

CD8 (C8/468)

CD8 is expressed by thymocytes and subpopulation of mature T cells and NK cells. CD8 is a cell surface receptor expressed as either as a heterodimer (CD8 alpha/beta) or a homodimer (CD8 alpha/alpha). It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Find out more about CD8

ERα (ESR1/1935)

Estrogen Receptor alpha (ERa) monoclonal is specific to ER alpha chain and shows minimal cross-reactivity with other members of estrogen receptor family of proteins. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen therapy. It strongly stains nuclei of epithelial cells in breast carcinomas. Find out more about ERα 


dsDNA (121-3)

Double-stranded (ds) DNA mouse monoclonal is a unique antibody that can be used as a nuclear marker. This antibody recognizes the double-stranded DNA in human cells and may be useful in identification of organelles in cells and tissues. dsDNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics. Find out more about dsDNA

CD61/Integrin b3 (ITGB3/2145)

CD61, also known as integrin b3, is a type I integral transmembrane protein. Integrin family of proteins is known to participate in cell adhesion as well as cell surface mediated signaling. CD61 plays a role in aggregations by interaction with various ligands like fibronectin, fibrinogen, von Willebrand factor, vitronectin, and thrombospondin. Find out more about CD61/Integrin b3

Cytokeratin 16 (KRT16/2043)

The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Cytokeratin 16 co-express with cytokeratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck. Find out more about Cytokeratin 16

BioGenex is offering these new antibodies in different formats: - ready-to-use (RTU) vials for manual staining and bar-coded vials for the i6000® and Xmatrx® family of automated staining systems. They are also available in concentrated format along with the antibody diluent (#HK156) and are also compatible with third-party detection systems.

“Introduction of these antibodies for cancer diagnostics demonstrates our commitment towards ‘Accelerating the Pace of Precision Medicine’. We are determined and will continue to bring quality products to our customers,” said Krishan Kalra Ph.D. CEO of BioGenex. 

About BioGenex Laboratories

BioGenex designs develop and commercialize fully-automated molecular pathology systems for cancer diagnosis, prognosis, personalized medicine, and life science research. Our fully-automated workstations are the most in-depth systems available globally. Our customer-focused approach, with excellent technical and customer support provides a unique and powerful service for pathology labs. Our spirit of innovation drives us to deliver cutting edge technology, years ahead of our competition, and the finest systems for Life Science research and diagnostics.

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